Rabbit anti Human CBWD2 Antibody, Polyclonal, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Function Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them. Catalyzes zinc insertion into the active site of methionine aminopeptidase METAP1, which function to cleave the initiator methionine from polypeptides during or after protein translation. Mechanistically, the N-terminal psi-PxLVp motif binds to the C6H2-type zinc finger of inactive form of METAP1. After formation of the docked complex, zinc is transferred from the CXCC motif in the GTPase domain of ZNG1B to the zinc binding site in the peptidase domain of METAP1 in a process requiring GTP hydrolysis. GTP/GDP exchange is required for release of active METAP1.
规格
产品名称
CBWD2 Antibody
别名
锌调节GTP酶金属蛋白激活剂1B抗体
英文别名
CBWD2_HUMAN antibody | Cobalamin synthase W domain-containing protein 2 antibody | Cobalamin synthetase W domain-containing protein 2 antibody | COBW domain-containing protein 2 antibody | ZNG1B | CBWD2 | CBWD2 antibody
规格或纯度
ExactAb™, Validated, 1.0 mg/mL
宿主种属
兔(Rabbit)
特异性
ZNG1B
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human CBWD2 (AA 108-158)
CBWD2 Antibody (Ab093328) - Western Blot All lanes: CBWD2 Antibody (Ab093328) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 43 kDa Observed band size: 42 kDa Exposure time: 30.0 s