Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). May target monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to plasma membranes of retinal pigment epithelium and neural retina. Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
宿主种属
兔(Rabbit)
特异性
BSG
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human CD147 (AA 181-194)
阳性对照
WB: HeLa, Ramos, Hep G2, HT-29, A549, NIH/3T3 and C6 cell lysates. IHC: Human colon cancer tissue. IF/ICC: HeLa cells.
Recombinant CD147 Antibody (Ab093918) - Western Blot All lanes: Recombinant CD147 Antibody (Ab093918) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 42 kDa Observed band size: 52, 60 kDa Exposure time: 30.0 s
Recombinant CD147 Antibody (Ab093918) - IF/ICC Immunocytochemistry analysis of CD147 (green) in Hela using Recombinant CD147 Antibody (Ab093918) and DAPI (blue).
Recombinant CD147 Antibody (Ab093918) - IHC Immunohistochemistry analysis of paraffin-embedded Human colon cancer tissue using Recombinant CD147 Antibody (Ab093918). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.