Rabbit anti Human Collagen XVII Antibody, Recombinant, could be used for WB, IHC, ICC, IF and so on. Application: WB: 1/500-1/2000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 Protein Relevance: Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in the gene coding for collagen XVII are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD 1, is generated by proteolytic processing of the full length form. Two transcript variants, one resulting from alternative splicing in the 3' UTR, have been identified for this gene.
规格
产品名称
重组XVII型胶原蛋白抗体
别名
胶原蛋白17抗体 | ⅩⅦ型胶原抗体 | Collagen XVII抗体 | 重组胶原蛋白 XVII 抗体
Recombinant Collagen XVII Antibody (Ab097237) - Western Blot All lanes: Recombinant Collagen XVII Antibody (Ab097237) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 150 kDa Observed band size: 182 kDa Exposure time: 27.9 s
Recombinant Collagen XVII Antibody (Ab097237) - IF/ICC Immunofluorescent analysis of A431 cells, using Recombinant Collagen XVII Antibody (Ab097237).
Recombinant Collagen XVII Antibody (Ab097237) - IHC Immunohistochemical analysis of paraffin-embedded mouse skin, using Recombinant Collagen XVII Antibody (Ab097237).