Rabbit anti Human CTDSP1 Antibody, Polyclonal, could be used for WB, IHC and so on.
Application
WB: 1/500-1/1000
IHC: 1/50-1/100
Protein Function
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
规格
产品名称
CTDSP1 Antibody
别名
羧基端小结构域磷酸酶1抗体 | CTDSP1抗体
英文别名
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 antibody | Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1 antibody | CTD (carboxy terminal domain RNA polymerase II polypeptide A) small phosphatase 1
规格或纯度
ExactAb™, Validated, Carrier Free, 1.0 mg/mL
宿主种属
兔(Rabbit)
特异性
CTDSP1
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human CTDSP1.
阳性对照
WB: Mouse skeletal muscle, Mouse spleen, Rat spleen, A549, HeLa, HEL and NIH/3T3 lysates. IHC: Human breast cancer tissue.
CTDSP1 Antibody (Ab098042) - Western Blot All lanes: CTDSP1 Antibody (Ab098042) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/10000 dilution Predicted band size: 29 kDa Observed band size: 28 kDa Exposure time: 33.0 s
CTDSP1 Antibody (Ab098042) - IHC Immunohistochemical analysis of CTDSP1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with CTDSP1 Antibody (Ab098042) at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.