ExactAb™,已验证,无叠氮钠,无载体 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Rabbit anti Human CTNNA1 Antibody, Polyclonal, could be used for WB, IHC, ICC/IF and so on.
Application
WB: 0.5-2 µg/mL IHC: 5-20 µg/mL ICC/IF: 5-20 μg/mL
Protein Function
Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
CTNNA1 Antibody (Ab098106) - Western Blot
All lanes: CTNNA1 Antibody (Ab098106) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 100 kDa
Observed band size: 103 kDa
Exposure time: 58.4 s
CTNNA1 Antibody (Ab098106) - IF/ICC
FITC staining on IF
4% paraformaldehyde-fixed HeLa (human epithelial cell line from cervix adenocarcinoma) cells stained for CTNNA1 (green) using CTNNA1 Antibody (Ab098106) at 20μg/mL in ICC/IF.
CTNNA1 Antibody (Ab098106) - IHC
DAB staining on IHC
Samples: Human Stomach Tissue
Primary Ab: 10 µg/mL CTNNA1 Antibody (Ab098106)
Second Ab: 2 µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody.
5-20 µg/mL
5-20 µg/mL
0.5-2µg/mL
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F1011937 |
分析证书 | Ab098106 |
| ZJ23F1101698 |
分析证书 | Ab098106 |
| ZJ23F1101699 |
分析证书 | Ab098106 |
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