Rabbit anti Human DYRK2 Antibody, Polyclonal, could be used for WB and so on. Application WB: 1/500-1/2000 Protein Function Role in the regulation of cellular growth and/or development. Regulates TP53 by phosphorylation on Ser-46 to induce apoptosis in response to DNA damage, functioning downstream of ATM. Inactivates GYS1 by phosphorylation at Ser-641, and potentially also a second phosphorylation site, thus regulating glycogen synthesis. Phosphorylates EIF2B5 at Ser-544, enabling its subsequent phosphorylation and inhibition by GSK3, and may play a more general role in the priming of GSK3 substrates.
DYRK2 Antibody (Ab100682) - Western Blot All lanes: DYRK2 Antibody (Ab100682) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/20000 dilution
Predicted band size: 67 kDa Observed band size: 67 kDa Exposure time: 92.0 s
DYRK2 Antibody (Ab100682) - Western Blot All lanes: DYRK2 Antibody (Ab100682) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/20000 dilution
Predicted band size: 67 kDa Observed band size: 67 kDa Exposure time: 92.0 s