Rabbit anti Human E3 ubiquitin-protein ligase MUL1 Antibody, Polyclonal, could be used for WB and so on. Application WB: 1/500-1/2000 Protein Function Exhibits weak E3 ubiquitin-protein ligase activity, but preferentially acts as a SUMO E3 ligase at physiological concentrations. Plays a role in the control of mitochondrial morphology. Promotes mitochondrial fragmentation and influences mitochondrial localization. Inhibits cell growth. When overexpressed, activates JNK through MAP3K7/TAK1 and induces caspase-dependent apoptosis. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
E3 ubiquitin-protein ligase MUL1 Antibody (Ab100808) - Western Blot All lanes: E3 ubiquitin-protein ligase MUL1 Antibody (Ab100808) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 40 kDa Observed band size: 36 kDa Exposure time: 10.0 s