Involved primarily in ATP hydrolysis at the plasma membrane. Plays a role in regulating pyrophosphate levels, and functions in bone mineralization and soft tissue calcification. In vitro, has a broad specificity, hydrolyzing other nucleoside 5' triphosphates such as GTP, CTP, TTP and UTP to their corresponding monophosphates with release of pyrophosphate and diadenosine polyphosphates, and also 3',5'-cAMP to AMP. May also be involved in the regulation of the availability of nucleotide sugars in the endoplasmic reticulum and Golgi, and the regulation of purinergic signaling. Appears to modulate insulin sensitivity.
宿主种属
小鼠(Mouse)
特异性
ENPP1/PC1
种属反应性
人(Human)
免疫原
Recombinant protein fragment of human ENPP1 produced in E.coli
ENPP1/PC1 Mouse mAb (Ab101725) - Western Blot All lanes: ENPP1/PC1 Mouse mAb (Ab101725) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 100 kDa Observed band size: 134 kDa Exposure time: 100.0 s
ENPP1/PC1 Mouse mAb (Ab101725) - Western Blot All lanes: ENPP1/PC1 Mouse mAb (Ab101725) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/10000 dilution
Predicted band size: 100 kDa Observed band size: 131 kDa Exposure time: 91.1 s
ZJ25F0117042
危险品化学品经营许可证（带存储）