ExactAb™,已验证 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 1 篇同行评审文献引用。
Mouse anti Human HDAC4 Antibody, Monoclonal antibody(4A3-H7-C6), could be used for WB, IP and so on.
Application:
WB: 1/500-1/1000
IP: 1/20
Protein Function
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
Post-translational
Phosphorylated by CaMK4 at Ser-246, Ser-467 and Ser-632. Phosphorylation at other residues is required for the interaction with 14-3-3. Sumoylation on Lys-559 is promoted by the E3 SUMO-protein ligase RANBP2, and prevented by phosphorylation by CaMK4.
HDAC4 Mouse mAb (Ab107057) - Western Blot
All lanes: HDAC4 Mouse mAb (Ab107057) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 119 kDa
Observed band size: 134 kDa
Exposure time: 60.0 s
HDAC4 Mouse mAb (Ab107057) - Western Blot
All lanes: HDAC4 Mouse mAb (Ab107057) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Mouse IgG H&L (HRP) (Ab179001) at 1/20000 dilution
Predicted band size: 119 kDa
Observed band size: 134 kDa
Exposure time: 30.0 s
HDAC4 Mouse mAb (Ab107057) - Western Blot
Immunoprecipitation analysis of HDAC4 in HeLa lysates using HDAC4 Mouse mAb (Ab107057)
1/500-1/1000
1/20
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0404334 |
分析证书 | Ab107057 |
| ZJ24F0404335 |
分析证书 | Ab107057 |
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