ExactAb™,已验证 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Rabbit anti Human hnRNP D Antibody, Polyclonal, could be used for WB, IHC, ICC, IF and so on.
Application:
WB: 1/500-1/2000
IHC: 1/100-1/300
ICC/IF: 1/200-1/1000
Protein Function
Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.
hnRNP D/AUF1 Antibody (Ab108424) - Western Blot
All lanes: hnRNP D/AUF1 Antibody (Ab108424) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 38 kDa
Observed band size: 35 kDa
Exposure time: 39.8 s
hnRNP D/AUF1 Antibody (Ab108424) - IF/ICC
Immunofluorescence analysis of HeLa cells, using hnRNP D/AUF1 Antibody (Ab108424). The picture on the right is blocked with the synthesized peptide.
hnRNP D/AUF1 Antibody (Ab108424) - IHC
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using hnRNP D/AUF1 Antibody (Ab108424). The picture on the right is blocked with the synthesized peptide.
1/500-1/2000
1/200 - 1/1000
1/100-1/300
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0405014 |
分析证书 | Ab108424 |
| ZJ24F0405015 |
分析证书 | Ab108424 |
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