Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.
宿主种属
兔(Rabbit)
特异性
HNRNPM
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human hnRNP M (AA 250-300).
阳性对照
WB: HeLa, Jurkat, Hep G2, MCF7, SH-SY5Y, NIH/3T3 and C6 cell lysates.
Recombinant hnRNP M1-M4 Antibody (Ab108459) - Western Blot All lanes: Recombinant hnRNP M1-M4 Antibody (Ab108459) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 78 kDa Observed band size: 75,78 kDa Recombinant hnRNP M1-M4 Antibody (Ab108459) may recognize two isoforms of hnRNP M1-M4. Exposure time: 22.5 s
Recombinant hnRNP M1-M4 Antibody (Ab108459) - Western Blot All lanes use the Antibody at 1/1000 dilution for 1 hour at room temperature.