Antigen identified by monoclonal antibody Ki 67 antibody | Antigen identified by monoclonal antibody Ki-67 antibody | Antigen KI-67 antibody | Antigen KI67 antibody | KI67_HUMAN antibody | KIA antibody | Marker of proliferation Ki-67 antibody | MIB 1 anti
规格或纯度
无载体, ExactAb™, 无叠氮钠, 已验证, 见COA
生化机理
Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. Does not contribute to the internal structure of mitotic chromosomes (By similarity). May play a role in chromatin organization. It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed.
宿主种属
小鼠(Mouse)
特异性
Ki67
种属反应性
人(Human)
免疫原
Peptide
阳性对照
IHC: Human tonsil tissue.
偶联
Unconjugated
克隆类型
单克隆抗体
克隆号
YN00996m
Format
Whole IgG
亚型
Mouse IgG
轻链亚型
kappa
纯化方法
Protein G purified
浓度
见COA
分子类型
抗体
产品线
生物产品
储存与运输
物理外观
Liquid
储存缓冲液
10mM TBS, Glycerol, 0.1% Proclin 300, pH7.4
防腐剂
0.1% Proclin 300
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
-20℃长期保存（12 个月）。收货后建议分装。避免冷冻/解冻循环。
图片
Ki67 Mouse mAb (Ab112020) - IHC Immunohistochemistry analysis of paraffin-embedded human tonsil tissue labelling Ki67 with Ki67 Mouse mAb (Ab112020) at 1/400 dilution. The section was incubated with Ki67 Mouse mAb (Ab112020) for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.
ZJ24F0707879
危险品化学品经营许可证（带存储）