Anti-LDL Receptor antibody | FH antibody | FHC antibody | LDL R antibody | LDL receptor antibody | LDLCQ2 antibody | Ldlr antibody | LDLR_HUMAN antibody | Low Density Lipoprotein Receptorantibody | Low density lipoprotein receptor class A domain containin
规格或纯度
见COA
生化机理
Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. In case of HIV-1 infection, functions as a receptor for extracellular Tat in neurons, mediating its internalization in uninfected cells.
Post-translational: N- and O-glycosylated. Ubiquitinated by MYLIP leading to degradation.
宿主种属
小鼠(Mouse)
特异性
LDLR
种属反应性
人(Human)
免疫原
Recombinant protein of human LDLR (AA 1-860).
阳性对照
WB: Human liver lysates. Flow Cytometry: 293T cells.