ExactAb™,已验证,重组 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Rabbit anti Human Mad2L2/REV7 Antibody, Recombinant, could be used for WB, IF, ICC and so on.
Application:
WB: 1/500-1/1000
ICC/IF: 1/50-1/200
Protein Function：
Adapter protein able to interact with different proteins and involved in different biological processes. Mediates the interaction between the error-prone DNA polymerase zeta catalytic subunit REV3L and the inserter polymerase REV1, thereby mediating the second polymerase switching in translesion DNA synthesis. Translesion DNA synthesis releases the replication blockade of replicative polymerases, stalled in presence of DNA lesions. May also regulate another aspect of cellular response to DNA damage through regulation of the JNK-mediated phosphorylation and activation of the transcriptional activator ELK1. Inhibits the FZR1- and probably CDC20-mediated activation of the anaphase promoting complex APC thereby regulating progression through the cell cycle. Regulates TCF7L2-mediated gene transcription and may play a role in epithelial-mesenchymal transdifferentiation.
Recombinant Mad2L2/REV7 Antibody (Ab113958) - Western Blot
All lanes: Recombinant Mad2L2/REV7 Antibody (Ab113958) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 24 kDa
Observed band size: 24 kDa
Exposure time: 30.0 s
Recombinant Mad2L2/REV7 Antibody (Ab113958) - IF/ICC
Immunocytochemistry analysis of Mad2L2/REV7 (green) in HeLa using Recombinant Mad2L2/REV7 Antibody (Ab113958), and cells were counterstained with DAPI (blue).
1/500-1/1000
1/50-1/200
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0506096 |
分析证书 | Ab113958 |
| ZJ24F0506097 |
分析证书 | Ab113958 |
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查看 Recombinant 级别指南 → 查看 Validated 级别指南 → 查看 ExactAb™ 级别指南 →
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