Role in epithelial morphogenesis. Modulates the developmental decision to build a columnar versus a hepatic epithelial cell apparently by promoting a switch from a direct to a transcytotic mode of apical protein delivery. Essential for the asymmetric development of membrane domains of polarized epithelial cells. One or more isoforms may play a role in graft rejection.
宿主种属
兔(Rabbit)
特异性
MARK2
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human MARK2 (AA 700-788)
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
图片
Recombinant MARK2 Antibody (Ab114281) - Western Blot All lanes: Recombinant MARK2 Antibody (Ab114281) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 78 kDa Observed band size: 82, 89 kDa MARK2 has 16 isoforms produced by alternative promoter usage and alternative splicing with the molecular mass of 78 - 90 kDa. Exposure time: 120.0 s
Recombinant MARK2 Antibody (Ab114281) - Western Blot All lanes: Recombinant MARK2 Antibody (Ab114281) at 1/1000 dilution Samples: Lysates at 10 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 78 kDa Observed band size: 85 kDa MARK2 has 16 isoforms produced by alternative promoter usage and alternative splicing with the molecular mass of 78 - 90 kDa. Exposure time: 100.0 s