ExactAb™,已验证,重组 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Rabbit anti Human MBD2 Antibody, Recombinant, could be used for WB, IHC, IF, ICC and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
IF/ICC: 1/50-1/200
Protein Function
Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
Recombinant MBD2 Antibody (Ab114412) - Western Blot
All lanes: Recombinant MBD2 Antibody (Ab114412) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 43 kDa
Observed band size: 30, 47 kDa.
Recombinant MBD2 Antibody (Ab114412) recognizes two isoforms of MBD2. The observed MW is consistent with what has been described in the literature (PMID: 17353267).
Exposure time: 20.0 s
Recombinant MBD2 Antibody (Ab114412) - IF/ICC
Immunocytochemistry analysis of MBD2 (green) in HL-60 using Recombinant MBD2 Antibody (Ab114412), and DAPI(blue).
Recombinant MBD2 Antibody (Ab114412) - IHC
Immunohistochemistry analysis of paraffin-embedded Human tonsil using Recombinant MBD2 Antibody (Ab114412). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
1/500-1/1000
1/50 - 1/100
1/50-1/200
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0506100 |
分析证书 | Ab114412 |
| ZJ24F0506101 |
分析证书 | Ab114412 |
我们的级别选择指南涵盖了目录中所有的变体的纯度、稳定剂状态和应用适用性。
查看 Recombinant 级别指南 → 查看 Validated 级别指南 → 查看 ExactAb™ 级别指南 →
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