Rabbit anti Human Melanoma gp100 Antibody, Recombinant, could be used for WB, IHC and so on. Application: WB: 1/500-1/2000 IHC: 1/50-1/200 Protein Function: Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity.
Recombinant Melanoma gp100 Antibody (Ab114936) - Western Blot Western blot analysis of Recombinant Melanoma gp100 Antibody (Ab114936) expression in human melanoma lysate.
Predicted band size: 70 kDa Observed band size: 100 & 26 kDa The gp100 protein exhibits different cleavage forms in melanoma cells. In one study (PMID: 15096515), gp100 was detected in the melanoma cell line MNT-1 as two major specific bands, measuring 100 kDa and 26 kDa.
Recombinant Melanoma gp100 Antibody (Ab114936) - IHC Immunohistochemical analysis of paraffin-embedded human melanoma, using Recombinant Melanoma gp100 Antibody (Ab114936).