Rabbit anti Human Menin Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/1000-1/2000 Protein Function: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.
Recombinant Menin Antibody (Ab114972) - Western Blot All lanes: Recombinant Menin Antibody (Ab114972) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/20000 dilution Predicted band size: 67 kDa Observed band size: 75, 64 kDa Recombinant Menin Antibody (Ab114972) recognizes different isoforms of Menin. Exposure time: 114.7 s