Rabbit anti Human MTH1 Antibody, Recombinant, could be used for WB, IF/ICC and so on.
Application: WB: 1/500-1/1000 IF/ICC:1/50-1/200
Protein Function: Antimutagenic. Acts as a sanitizing enzyme for oxidized nucleotide pools, thus suppressing cell dysfunction and death induced by oxidative stress. Hydrolyzes 8-oxo-dGTP, 8-oxo-dATP and 2-OH-dATP, thus preventing misincorporation of oxidized purine nucleoside triphosphates into DNA and subsequently preventing A:T to C:G and G:C to T:A transversions. Able to hydrolyze also the corresponding ribonucleotides, 2-OH-ATP, 8-oxo-GTP and 8-oxo-ATP. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.
Recombinant MTH1 Antibody (Ab116266) - Western Blot All lanes: Recombinant MTH1 Antibody (Ab116266) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 18 kDa Observed band size: 18 kDa Exposure time: 1.0 s
Recombinant MTH1 Antibody (Ab116266) - IF/ICC Immunocytochemistry analysis of MTH1 (green) in HeLa using Recombinant MTH1 Antibody (Ab116266), and cells were counterstained with DAPI (blue).