Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. g pathway (TLR) in dendritic cells: required for acute TLR-induced macropinocytosis by phosphorylating and activating RPS6KA3. Also acts as a modulator of Polycomb-mediated repression.
宿主种属
兔(Rabbit)
特异性
MYD88
种属反应性
人(Human)
免疫原
A synthetic peptide derived from human MyD88 (AA 1-48).
阳性对照
WB: Raji, A549, THP-1, Jurkat, Hep G2 and K562 cell lysates. IHC: Human breast cancer tissue. ICC/IF: A549 cells.
Recombinant MyD88 Antibody (Ab116645) - Western Blot All lanes: Recombinant MyD88 Antibody (Ab116645) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 33 kDa Observed band size: 31 kDa Exposure time: 233.9 s
Recombinant MyD88 Antibody (Ab116645) - IF/ICC Immunofluorescence analysis of MyD88 in A549 using Recombinant MyD88 Antibody (Ab116645).
Recombinant MyD88 Antibody (Ab116645) - IHC Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Recombinant MyD88 Antibody (Ab116645). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
ZJ24F0303445
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