Rabbit anti Human Myelin Basic Protein Antibody, Recombinant (EP207), could be used for IHC and so on. Application IHC: 1/50-1/100 Protein Function The classic group of MBP isoforms (isoform 4-isoform 14) are with PLP the most abundant protein components of the myelin membrane in the CNS. They have a role in both its formation and stabilization. The smaller isoforms might have an important role in remyelination of denuded axons in multiple sclerosis. The non-classic group of MBP isoforms (isoform 1-isoform 3/Golli-MBPs) may preferentially have a role in the early developing brain long before myelination, maybe as components of transcriptional complexes, and may also be involved in signaling pathways in T-cells and neural cells. Differential splicing events combined with optional post-translational modifications give a wide spectrum of isomers, with each of them potentially having a specialized function. Induces T-cell proliferation.
A synthetic peptide corresponding to residues of Myelin Basic Protein (AA 150-250).
阳性对照
IHC: Human glioma tissue.
偶联
Unconjugated
克隆类型
重组抗体
克隆号
EP207
Format
Whole IgG
亚型
Rabbit IgG
纯化方法
Protein A purified
浓度
0.075 mg/mL
分子类型
抗体
产品线
生物产品
储存与运输
物理外观
Liquid
储存缓冲液
10mM PBST, 0.015% Sodium azide, pH 7.4
防腐剂
0.015% Sodium azide
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
4℃ 短期储存(1-2 周)。-20℃长期保存(12 个月)。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Myelin Basic Protein Antibody (Ab116662) - IHC Immunohistochemistry analysis of paraffin-embedded human glioma tissue labelling Myelin Basic Protein with Recombinant Myelin Basic Protein Antibody (Ab116662) at 1/100 dilution. The section was incubated with Ab116662 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.