Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
Post-translational: Cleaved by CORIN upon secretion to produce the functional hormone. Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity.
宿主种属
兔(Rabbit)
特异性
NPPA
种属反应性
人(Human)
免疫原
A synthetic peptide derived from human Natriuretic peptides A (AA 100-151).
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
图片
Recombinant Natriuretic peptides A Antibody (Ab117136) - Western Blot All lanes: Recombinant Natriuretic peptides A Antibody (Ab117136) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/5000 dilution Predicted band size: 16 kDa Observed band size: 15 kDa Exposure time: 120.0 s
ZJ25F0420692
危险品化学品经营许可证（带存储）