Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells. Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function (By similarity).
宿主种属
兔(Rabbit)
特异性
NFAT2
种属反应性
人(Human)
免疫原
A synthetic peptide derived from human NFAT2 (AA 900-943).
Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
图片
Recombinant NFAT2 Antibody (Ab117841) - Western Blot All lanes: Recombinant NFAT2 Antibody (Ab117841) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/40000 dilution Predicted band size: 101 kDa Observed band size: 113 kDa Exposure time: 100.0 s