NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.
宿主种属
兔(Rabbit)
特异性
GRIN1
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human GluN1 (AA 850-900)
Recombinant NMDAR1 Antibody (Ab118275) - Western Blot All lanes: Recombinant NMDAR1 Antibody (Ab118275) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 105 kDa Observed band size: 68, 72, 79, 108, 116 kDa Exposure time: 36.4 s