Nucleolin is the major nucleolar protein of growing eukaryotic cells. It is found associated with intranucleolar chromatin and pre-ribosomal particles. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. May play a role in the process of transcriptional elongation. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats.
宿主种属
兔(Rabbit)
特异性
NCL
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
预测反应种属
苏门答腊猩猩(Sumatran orangutan),食蟹猴(Cynomolgus monkey)
免疫原
A synthetic peptide derived from human Nucleolin (AA 670-710)
Recombinant Nucleolin Antibody (Ab118892) - Western Blot All lanes: Recombinant Nucleolin Antibody (Ab118892) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 77 kDa Observed band size: 98 kDa Exposure time: 6.9 s
ZJ25F0319238
危险品化学品经营许可证（带存储）