ExactAb™,已验证,重组 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Rabbit anti Human Phospholamban Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500 - 1/1000
Protein Function
Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. ATP2A2 inhibition is alleviated by PLN phosphorylation.
Post-translational
Phosphorylation by PKA abolishes the inhibition of ATP2A2-mediated calcium uptake. Phosphorylated at Thr-17 by CaMK2, and in response to beta-adrenergic stimulation. Phosphorylation by DMPK may stimulate sarcoplasmic reticulum calcium uptake in cardiomyocytes.
Recombinant Phospholamban Antibody (Ab121644) - Western Blot
All lanes: Recombinant Phospholamban Antibody (Ab121644) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 6 kDa
Observed band size: 13 kDa
Exposure time: 4.4 s
1/500-1/1000
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ25F0318746 |
分析证书 | Ab121644 |
| ZJ25F0318745 |
分析证书 | Ab121644 |
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