Plays a role in actin reorganization and cell migration. The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. Major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase.
宿主种属
兔(Rabbit)
特异性
PLCG1
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
预测反应种属
牛(Cow)
免疫原
A synthetic peptide derived from human PLCG1 (AA 750-810).
阳性对照
WB: Rat brain, HeLa, SH-SY5Y, Hep G2 and Jurkat lysates. IF/ICC: HeLa cells.
Recombinant Phospholipase C gamma 1/PLC-gamma-1 Antibody (Ab121687) - Western Blot All lanes: Recombinant Phospholipase C gamma 1/PLC-gamma-1 Antibody (Ab121687) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/40000 dilution
Predicted band size: 149 kDa Observed band size: 150 kDa Exposure time: 114.2 s
Recombinant Phospholipase C gamma 1/PLC-gamma-1 Antibody (Ab121687) - Western Blot All lanes: Recombinant Phospholipase C gamma 1/PLC-gamma-1 Antibody (Ab121687) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 149 kDa Observed band size: 150 kDa Exposure time: 100.0 s
Recombinant Phospholipase C gamma 1/PLC-gamma-1 Antibody (Ab121687) - IF/ICC Immunofluorescent analysis of HeLa cells, using Recombinant Phospholipase C gamma 1/PLC-gamma-1 Antibody (Ab121687) at 1/50 dilution.