Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzing pSer/Thr-Pro cis/trans isomerizations.
Post-translational: Phosphorylated upon DNA damage, probably by ATM or ATR.
宿主种属
兔(Rabbit)
特异性
PIN1
种属反应性
人(Human),仓鼠(Hamster),大鼠(Rat),小鼠(Mouse)
免疫原
Recombinant protein of human Pin1 (AA 1-165)
阳性对照
WB: Jurkat, HeLa, MCF7, Raji, HEK293, NIH/3T3 and C6 cell lysates. IHC: Human breast cancer tissue. ICC/IF: HEK293 cells.
Recombinant Pin1 Antibody (Ab121891) - Western Blot All lanes: Recombinant Pin1 Antibody (Ab121891) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 18 kDa Observed band size: 17 kDa Exposure time: 14.3 s
Recombinant Pin1 Antibody (Ab121891) - IF/ICC Immunocytochemistry analysis of PIN1 (green) in 293 using Recombinant Pin1 Antibody (Ab121891), and DAPI (blue).
Recombinant Pin1 Antibody (Ab121891) - IHC Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Recombinant Pin1 Antibody (Ab121891). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
ZJ24F0506150
危险品化学品经营许可证（带存储）