这是一种钙依赖型、磷脂依赖型、丝氨酸和苏氨酸特异性酶。对 T 细胞受体(TCR)介导的 T 细胞活化至关重要,但在依赖 TCR 的胸腺细胞发育过程中却不可或缺。将 TCR 信号复合体与成熟 T 淋巴细胞中 NF-kappa-B 的激活联系起来。白细胞介素-2(IL2)的产生需要它。PKC 被二酰甘油激活,进而使一系列细胞蛋白磷酸化。PKC 也是一类肿瘤促进剂--薄荷醇酯的受体。
宿主种属
兔(Rabbit)
特异性
PRKCQ
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human PKC theta (AA 600-650)
Recombinant PKC theta Antibody (Ab122106) - Western Blot All lanes: Recombinant PKC theta Antibody (Ab122106) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 82 kDa Observed band size: 61 - 90 kDa The expression profile and molecular weight observed may be due to post-translational modifications or Recombinant PKC theta Antibody (Ab122106) can recognize different isoforms of PKC theta. Exposure time: 6.7 s