ExactAb™,已验证,重组 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Rabbit anti Human PPP1CB Antibody, Recombinant, could be used for WB, IHC, ICC/IF and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
ICC/IF: 1/50-1/200
Protein Function
Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).
Recombinant PPP1CB Antibody (Ab122822) - Western Blot
All lanes: Recombinant PPP1CB Antibody (Ab122822) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 37 kDa
Observed band size: 35 kDa
Exposure time: 7.2 s
Recombinant PPP1CB Antibody (Ab122822) - IF/ICC
Immunocytochemistry analysis of PPP1CB (green) in HeLa using Recombinant PPP1CB Antibody (Ab122822), and cells were counterstained with DAPI (blue).
Recombinant PPP1CB Antibody (Ab122822) - IHC
Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Recombinant PPP1CB Antibody (Ab122822). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
1/50 - 1/100
1/50-1/200
1/500-1/1000
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0202784 |
分析证书 | Ab122822 |
| ZJ24F0202783 |
分析证书 | Ab122822 |
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