ExactAb™,已验证,重组 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Rabbit anti Human Presenilin 1/PS-1 Antibody, Recombinant, could be used for WB, IF, ICC and so on.
Application:
WB: 1/500-1/1000
ICC/IF: 1/50-1/200
Protein function
Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. Stimulates cell-cell adhesion though its association with the E-cadherin/catenin complex. Under conditions of apoptosis or calcium influx, cleaves E-cadherin promoting the disassembly of the E-cadherin/catenin complex and increasing the pool of cytoplasmic beta-catenin, thus negatively regulating Wnt signaling. May also play a role in hematopoiesis.
Recombinant Presenilin 1/PS-1 Antibody (Ab123023) - Western Blot
All lanes: Recombinant Presenilin 1/PS-1 Antibody (Ab123023) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 19 kDa
Exposure time: 42.7 s
Recombinant Presenilin 1/PS-1 Antibody (Ab123023) - IF/ICC
Immunocytochemistry analysis of Presenilin 1 (green) in SKOV-3 using Recombinant Presenilin 1/PS-1 Antibody (Ab123023), and cells were counterstained with DAPI (blue).
1/500-1/1000
1/50-1/200
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0102518 |
分析证书 | Ab123023 |
| ZJ24F0102519 |
分析证书 | Ab123023 |
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查看 Recombinant 级别指南 → 查看 Validated 级别指南 → 查看 ExactAb™ 级别指南 →
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