HC2 | HEL-S-275 | NU | PROS30 | Proteasome subunit alpha type | Proteasome subunit alpha type-1 | Macropain Subunit C2 | P30-33K | PROS30 | Proteasome Component C2 | Proteasome nu Chain | PSC2 | PSMA1 | 30 kDa prosomal protein antibody | HC 2 antibody | H
规格或纯度
重组, ExactAb™, 已验证, 见COA
生化机理
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Mediates the lipopolysaccharide-induced signal transduction in the macrophage proteasome (By similarity). Might be involved in the anti-inflammatory response of macrophages during the interaction with C.albicans heat-inactivated cells.
宿主种属
兔(Rabbit)
特异性
Proteasome 20S C2/HC2
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
预测反应种属
食蟹猴(Cynomolgus monkey)
免疫原
A synthetic peptide derived from human PSMA1 (AA 210-263)
阳性对照
WB: Hep G2, HeLa, Jurkat, HEK293, NIH/3T3 and C6 cell lysates.
Recombinant Proteasome 20S C2/HC2 Antibody (Ab123390) - Western Blot All lanes: Recombinant Proteasome 20S C2/HC2 Antibody (Ab123390) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/20000 dilution
Predicted band size: 30 kDa Observed band size: 29 kDa Exposure time: 64.0 s