Rabbit anti Human RACK1 Antibody, Recombinant, could be used for WB, IHC and so on. Application: WB: 1/500-1/1000 IHC: 1/50-1/100 Protein Function: Seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and ITGB1, serves as a platform for SRC activation or inactivation. May play an important role in the developing brain and neuronal differentiation.
Cell proliferation-inducing gene 21 protein | Guanine nucleotide-binding protein subunit beta-2-like 1 | Guanine nucleotide-binding protein subunit beta-like protein 12.3 | HLC-7 | Human lung cancer oncogene 7 protein | Receptor for activated C kinase | S
规格或纯度
重组, ExactAb™, 已验证, 高性能, 见COA
生化机理
Seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1. Together with KRT1 and ITGB1, serves as a platform for SRC activation or inactivation. May play an important role in the developing brain and neuronal differentiation.
宿主种属
兔(Rabbit)
特异性
RACK1
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human RACK1 (AA 271-286)
阳性对照
WB: MCF7, THP-1, HEK293, Jutkat, NIH/3T3 and C6 cell lysates. IHC: Human breast cancer tissue.
Recombinant RACK1 Antibody (Ab124329) - Western Blot All lanes: Recombinant RACK1 Antibody (Ab124329) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 35 kDa Observed band size: 32 kDa Exposure time: 3.7 s
Recombinant RACK1 Antibody (Ab124329) - IHC Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Recombinant RACK1 Antibody (Ab124329). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.