Rabbit anti Human Ran Antibody, Recombinant, could be used for WB, ICC, IF and so on. Application: WB: 1/500-1/2000 ICC/IF: 1/50-1/200 Protein Function: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules. Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
Androgen receptor associated protein 24 antibody | Androgen receptor-associated protein 24 antibody | ARA 24 antibody | ARA24 antibody | Gsp1 antibody | GTP binding nuclear protein RAN antibody | GTP-binding nuclear protein Ran antibody | GTPase Ran antib
规格或纯度
ExactAb™, Validated, 重组, 1.2 mg/mL
宿主种属
兔(Rabbit)
特异性
Ran
种属反应性
人(Human),小鼠(Mouse),猴(Monkey)
免疫原
A synthetic peptide derived from human Ran (AA 191-204)
阳性对照
WB: Hep G2, HEK293, Raji, Jurkat, HeLa and RAW 264.7 cell lysates. ICC/IF: U87-MG cells.
Recombinant Ran Antibody (Ab124509) - Western Blot All lanes: Recombinant Ran Antibody (Ab124509) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution
Predicted band size: 24 kDa Observed band size: 26 kDa Exposure time: 10.0 s
Recombinant Ran Antibody (Ab124509) - IF/ICC Immunocytochemistry analysis of Ran (green) in U87-MG using Recombinant Ran Antibody (Ab124509), and cells were counterstained with DAPI (blue).
ZJ24F0404025
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