Rabbit anti Human RBM5 Antibody, Polyclonal, could be used for WB, IHC and so on. Application: WB: 1/500-1/1000 IHC: 1/50-1/100 Protein Function: Component of the spliceosome A complex. Regulates alternative splicing of a number of mRNAs. May modulate splice site pairing after recruitment of the U1 and U2 snRNPs to the 5' and 3' splice sites of the intron. May both positively and negatively regulate aopotosis by regulating the alternative splicing of several genes involved in this process, including FAS and CASP2/caspase-2. In the case of FAS, promotes exclusion of exon 6 thereby producing a soluble form of FAS that inhibits apoptosis. In the case of CASP2/caspase-2, promotes exclusion of exon 9 thereby producing a catalytically active form of CASP2/Caspase-2 that induces apoptosis.
RBM5 Antibody (Ab124796) - Western Blot All lanes: RBM5 Antibody (Ab124796) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 92 kDa Observed band size: 112 kDa Exposure time: 123.8 s. The RNA-binding protein forms a complex with the target protein, this may alter the effective molecular weight of the target protein, thereby affecting its migration speed in the gel. The formation of complexes may cause bands to migrate upward or downward.
RBM5 Antibody (Ab124796) - IHC Immunohistochemistry analysis of paraffin-embedded Human thyroid cancer using RBM5 Antibody (Ab124796). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
ZJ24F0709045
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