hBAP | BAP | Bap37 | BCAP37 | B-cell associated protein | D-Prohibitin | MGC117268 | p22 | PHB2 | PNAS-141 | Prohibitin 2 | prohibitin-2 | REA | REAB-cell receptor-associated protein BAP37 | Repressor of estrogen receptor activity | B cell receptor associ
规格或纯度
重组, ExactAb™, 已验证, 高性能, 见COA
生化机理
Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
宿主种属
兔(Rabbit)
特异性
REA
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human REA (AA 167-180)
阳性对照
WB: Hep G2, K562, HeLa, A431, NIH/3T3 and C6 cell lysates. ICC/IF: HeLa cells. IHC: Human colon cancer tissue.
Recombinant REA Antibody (Ab124898) - Western Blot All lanes: Recombinant REA Antibody (Ab124898) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/40000 dilution
Predicted band size: 33 kDa Observed band size: 32 kDa Exposure time: 15.0 s
Recombinant REA Antibody (Ab124898) - IF/ICC Immunocytochemistry analysis of REA (green) in HeLa using Recombinant REA Antibody (Ab124898), and cells were counterstained with DAPI (blue).
Recombinant REA Antibody (Ab124898) - IHC Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Recombinant REA Antibody (Ab124898). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
ZJ24F0303570
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