ExactAb™,已验证,重组 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Rabbit anti Human Rho A + B + C Antibody, Recombinant, could be used for WB, IHC, ICC, IF and so on.
Application:
WB: 1/500-1/2000
IHC: 1/500-1/1000
ICC/IF: 1/100-1/500
Protein Function
Rho A: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP.
Rho B: Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
Rho C: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers.
Recombinant Rho A + B + C Antibody (Ab125253) - Western Blot
All lanes: Recombinant Rho A + B + C Antibody (Ab125253) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 22 kDa
Observed band size: 23 kDa
Exposure time: 100.0 s
Recombinant Rho A + B + C Antibody (Ab125253) - IF/ICC
Immunofluorescent analysis of HeLa cells, using Recombinant Rho A + B + C Antibody (Ab125253).
Recombinant Rho A + B + C Antibody (Ab125253) - IHC
Immunohistochemical analysis of paraffin-embedded human lung carcinoma, using Recombinant Rho A + B + C Antibody (Ab125253).
1:500-1000
1/500-1/2000
1/100-1/500
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
|---|
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0708628 |
分析证书 | Ab125253 |
| ZJ24F0708630 |
分析证书 | Ab125253 |
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