ExactAb™,已验证,重组 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Rabbit anti Human RING2/RING1B/RNF2 Antibody, Recombinant, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
Protein Function:
E3 ubiquitin-protein ligase that mediates monoubiquitination of 'Lys-119' of histone H2A, thereby playing a central role in histone code and gene regulation. H2A 'Lys-119' ubiquitination gives a specific tag for epigenetic transcriptional repression and participates in × chromosome inactivation of female mammals. May be involved in the initiation of both imprinted and random × inactivation. Essential component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex act via chromatin remodeling and modification of histones, rendering chromatin heritably changed in its expressibility. E3 ubiquitin-protein ligase activity is enhanced by BMI1/PCGF4. Acts as the main E3 ubiquitin ligase on histone H2A of the PRC1 complex, while RING1 may rather act as a modulator of RNF2/RING2 activity.
Recombinant RING2/RING1B/RNF2 Antibody (Ab125386) - Western Blot
All lanes: Recombinant RING2/RING1B/RNF2 Antibody (Ab125386) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution
Predicted band size: 38 kDa
Observed band size: 41 kDa
Exposure time: 137.7 s
Recombinant RING2/RING1B/RNF2 Antibody (Ab125386) - Western Blot
All lanes: Recombinant RING2/RING1B/RNF2 Antibody (Ab125386) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution
Predicted band size: 38 kDa
Observed band size: 41 kDa
Exposure time: 60.0 s
Recombinant RING2/RING1B/RNF2 Antibody (Ab125386) - IHC
Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Recombinant RING2/RING1B/RNF2 Antibody (Ab125386). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
1/500-1/1000
1/50 - 1/100
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0607278 |
分析证书 | Ab125386 |
| ZJ24F0607279 |
分析证书 | Ab125386 |
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