Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier.
宿主种属
兔(Rabbit)
特异性
SCN2B
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse),狗(Dog)
免疫原
A KLH-conjugated synthetic peptide encompassing a sequence within the center region of human SCN2B.
Store at 4°C short term (1-2 weeks). Store at -20°C long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
图片
Scn2b Antibody (Ab126777) - Western Blot All lanes: Scn2b Antibody (Ab126777) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 24 kDa Observed band size: 22 kDa Exposure time: 80.0 s