Rabbit anti Human Skp1 Antibody, Recombinant, could be used for WB and so on.
规格
产品名称
Recombinant Skp1 Antibody
别名
S期激酶相关蛋白1抗体
英文别名
Cyclin A/CDK2 associated p19 | Cyclin A/CDK2 associated protein p19 | Cyclin-A/CDK2-associated protein p19 | EMC19 | MGC34403 | OCP 2 | OCP II | OCP II protein | OCP-2 | OCP-II | OCP2 | OCPII | Organ of Corti protein 2 | Organ of Corti protein II | OTTHUM
规格或纯度
重组, ExactAb™, 已验证, 见COA
生化机理
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110.
宿主种属
兔(Rabbit)
特异性
SKP1
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human Skp1 (AA 120-163)
阳性对照
WB: HeLa, HEK293, A549, MCF7, NIH/3T3 and C6 cell lysates.
Recombinant Skp1 Antibody (Ab127742) - Western Blot All lanes: Recombinant Skp1 Antibody (Ab127742) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 19 kDa Observed band size: 19 kDa Exposure time: 39.8 s
ZJ25F0117181
危险品化学品经营许可证（带存储）