ExactAb™,已验证,无载体 级 ，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Rabbit anti Human SOCS1 Antibody, Polyclonal antibody, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
IF/ICC: 1/200
Protein Function
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT3 pathway. Through binding to JAKs, inhibits their kinase activity. In vitro, also suppresses Tec protein-tyrosine activity. Appears to be a major regulator of signaling by interleukin 6 (IL6) and leukemia inhibitory factor (LIF). Regulates interferon-gamma mediated sensory neuron survival (By similarity). Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize JAK2.
SOCS1 Antibody (Ab128582) - Western Blot
All lanes: SOCS1 Antibody (Ab128582) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 24 kDa
Observed band size: 23 kDa
Exposure time: 10.2 s
SOCS1 Antibody (Ab128582) - IHC
Immunohistochemistry analysis of paraffin-embedded Human gastric cancer using SOCS1 Antibody (Ab128582). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
SOCS1 Antibody (Ab128582) - IF/ICC
IF analysis of SOCS1 Antibody (Ab128582) in HeLa cells. The cells were fixed and permeabilized with 100% methanol for 5 minutes, and blocked with 5% BSA for 1 hour at room temperature. Cells were stained with SOCS1 Antibody (Ab128582) at 1/200 dilution in blocking buffer overnight at 4°C, and then incubated with Goat Anti-Rabbit IgG H&L (AF647) (Ab181958) at a dilution of 1/1000 for 1 hour at room temperature in the dark (red). Cells were counterstained with DAPI (blue).
1/500-1/1000
1/50 - 1/100
1/200
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F0505984 |
分析证书 | Ab128582 |
| ZJ24F0505985 |
分析证书 | Ab128582 |
| ZJ24F0505986 |
分析证书 | Ab128582 |
| ZJ23F1202197 |
分析证书 | Ab128582 |
| ZJ23F1202206 |
分析证书 | Ab128582 |
| ZJ23F1202043 |
分析证书 | Ab128582 |
| ZJ23F1202044 |
分析证书 | Ab128582 |
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