OI17 | ON | ONT | Basement-membrane protein 40 | BM-40 | ONcysteine-rich protein | Osteonectin | Secreted protein acidic and rich in cysteine | secreted protein, acidic, cysteine-rich (osteonectin) | SPARC | AA517111 antibody | Basement membrane protein 4
规格或纯度
见COA
生化机理
Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca(2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
宿主种属
兔(Rabbit)
特异性
SPARC
种属反应性
人(Human),小鼠(Mouse)
免疫原
Fusion protein of human SPARC.
阳性对照
WB: U251 and A375 cell lysates. IHC: Human liver cancer tissue.