Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Play a direct role in facilitating neuronal migration.
宿主种属
兔(Rabbit)
特异性
Tissue Plasminogen Activator
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human tPA (AA 533-562)
Recombinant Tissue Plasminogen Activator Antibody (Ab131422) - Western Blot All lanes: Recombinant Tissue Plasminogen Activator Antibody (Ab131422) at 1/1000 dilution Samples: Lysates at 10 µL(1/100 dilution) per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution Predicted band size: 63 kDa Observed band size: 61 kDa Exposure time: 60.0 s