Rabbit anti Human TRPM8 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/1000-1/2000 Protein Function: Receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. Activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH. Involved in menthol sensation. Permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium. Temperature sensing is tightly linked to voltage-dependent gating. Activated upon depolarization, changes in temperature resulting in graded shifts of its voltage-dependent activation curves. The chemical agonists menthol functions as a gating modifier, shifting activation curves towards physiological membrane potentials. Temperature sensitivity arises from a tenfold difference in the activation energies associated with voltage-dependent opening and closing.
规格
产品名称
Recombinant TRPM8 Antibody
别名
“冷”蛋白TRPM8抗体
英文别名
LTrpC-6 | LTrpC6 antibody Short form of the TRPM8 cationic channel | Transient receptor potential cation channel subfamily M member 8 | Transient receptor potential p8 | Trp p8 | Trp-p8 | Trpm8 | TRPM8_HUMAN | TRPP8 | MGC2849 | transient receptor potentia
规格或纯度
重组, ExactAb™, 已验证, 见COA
宿主种属
兔(Rabbit)
特异性
TRPM8
种属反应性
人(Human),小鼠(Mouse)
免疫原
A synthetic peptide derived from human TRPM8 (AA 900-1000)
阳性对照
WB: HeLa, HEK293, MCF7, K562 and A549 cell lysates.
Recombinant TRPM8 Antibody (Ab132725) - Western Blot All lanes: Recombinant TRPM8 Antibody (Ab132725) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 128 kDa Observed band size: 116 kDa Exposure time: 60.0 s