N2441 antibody | OMP2 antibody | POR1 antibody | hVDAC1 antibody | MGC111064 antibody | Mitochondrial Porin antibody | Outer mitochondrial membrane protein porin 1 antibody | Plasmalemmal porin antibody | Porin 31HL antibody | Porin 31HM antibody | VDAC a
规格或纯度
ExactAb™, 已验证, 重组, 见COA
生化机理
Forms a channel through the mitochondrial outer membrane and also the plasma membrane. The channel at the outer mitochondrial membrane allows diffusion of small hydrophilic molecules; in the plasma membrane it is involved in cell volume regulation and apoptosis. It adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation-selective. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
宿主种属
兔(Rabbit)
特异性
VDAC1/Porin
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human VDAC1 (AA 1-66).
阳性对照
WB: Raji, HEK293, A431, HeLa, THP-1, Jurkat, Hep G2, NIH/3T3 and C6 cell lysates. IHC: Human liver, stomach, prostate cancer, Mouse intestine, skin tissue. IF/ICC: HeLa cells.
VDAC1/Porin Antibody (Ab133998) - Western Blot All lanes: VDAC1/Porin Antibody (Ab133998) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 31 kDa Observed band size: 31 kDa Exposure time: 16.3 s
VDAC1/Porin Antibody (Ab133998) - IHC Immunohistochemistry analysis of paraffin-embedded Human liver using VDAC1/Porin Antibody (Ab133998). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
VDAC1/Porin Antibody (Ab133998) - IHC Immunohistochemical analysis of paraffin-embedded Mouse intestine, using VDAC1/Porin Antibody (Ab133998) at 1/200 dilution.
VDAC1/Porin Antibody (Ab133998) - IHC Immunohistochemical analysis of paraffin-embedded Mouse skin, using VDAC1/Porin Antibody (Ab133998) at 1/200 dilution.
VDAC1/Porin Antibody (Ab133998) - IHC Immunohistochemical analysis of paraffin-embedded Human stomach, using VDAC1/Porin Antibody (Ab133998) at 1/200 dilution.
VDAC1/Porin Antibody (Ab133998) - IHC Immunohistochemical analysis of paraffin-embedded Human prostate cancer, using VDAC1/Porin Antibody (Ab133998) at 1/200 dilution.
VDAC1/Porin Antibody (Ab133998) - IF/ICC Immunofluorescent analysis of HeLa cells, using VDAC1/Porin Antibody (Ab133998) at 1/50 dilution.
ZJ24F0202793
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