Rabbit anti Human EMAP II/AIMP1 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/1000 Protein Function: Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glukagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
规格
产品名称
Recombinant EMAP II/AIMP1 Antibody
规格或纯度
重组,ExactAb™,已验证,PBS Only,见COA
宿主种属
兔(Rabbit)
特异性
AIMP1
种属反应性
人(Human),大鼠(Rat),小鼠(Mouse)
免疫原
A synthetic peptide derived from human EMAP II (AA 164-177)
阳性对照
WB: HeLa, HEK293, Hep G2, NIH/3T3 and C6 cell lysates.
Recombinant EMAP II/AIMP1 Antibody (Ab101549) - Western Blot All lanes: Recombinant EMAP II/AIMP1 Antibody (Ab101549) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 34 kDa Observed band size: 34 kDa Exposure time: 96.1 s
Recombinant EMAP II/AIMP1 Antibody (Ab101549) - Western Blot All lanes: Recombinant EMAP II/AIMP1 Antibody (Ab101549) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution Predicted band size: 34 kDa Observed band size: 32, 34 kDa Exposure time: 120.0 s