ExactAb™,低内毒素,已验证,无动物源,无叠氮钠,无载体,重组 级 提供 ≥95%(SDS-PAGE&SEC-HPLC) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 2 篇同行评审文献引用。
Amivantamab (anti-c-Met) 是一种人源 EGFR-MET 双特异性抗体，具有免疫抗癌活性。Amivantamab (anti-c-Met) 可以抑制配体结合，促进受体-抗体复合物的内吞作用和降解，并诱导巨噬细胞的 Fc 依赖性胞吞作用和自然杀伤细胞的抗体依赖性细胞毒性。
Amivantamab (anti-c-Met) is a human EGFR-MET bispecific antibody with immune anticancer activity. Amivantamab (anti-c-Met) inhibits ligand binding, promotes endocytosis and degradation of receptor-antibody complexes, and induces Fc-dependent cytokinesis in macrophages and antibody-dependent cytotoxicity in natural killer cells.
Amivantamab (anti-c-Met) (Ab175451) - Flow Cytometry
Flow Cytometry analysis of HepG2 cells labelling c-Met (red) with Amivantamab (anti-c-Met) (Ab175451). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Amivantamab (anti-c-Met) (Ab175451) - Flow Cytometry
Flow Cytometry analysis of MDA-MB-231 cells labelling c-Met (red) with Amivantamab (anti-c-Met) (Ab175451). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Amivantamab (anti-c-Met) (Ab175451) - SEC
The purity of Amivantamab (anti-c-Met) (Ab175451) is more than 95% verified by HPLC.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
 ZJ24F1114630 |
分析证书 | Ab175451 |
| ZJ24F0910006 |
分析证书 | Ab175451 |
| ZJ24F0910007 |
分析证书 | Ab175451 |
| ZJ24F0910008 |
分析证书 | Ab175451 |
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