计算溶液所需的质量、体积或浓度。
Ustekinumab (anti-IL-12&IL-23) (Ab175693) - ELISA
Immobilized Recombinant Human IL-12/IL-23 p40 protein (rp181556) at 1.0 μg/mL can bind Ustekinumab (anti-IL-12&IL-23) (Ab175693) with the EC₅₀ of 20.26 ng/mL.
ExactAb™,低内毒素,已验证,无动物源,无叠氮钠,无载体,重组 级 提供 ≥95%(SDS-PAGE&SEC-HPLC) 纯度,适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Ustekinumab (anti-IL-12&IL-23) 是一种抗 IL-12/IL-23 的人源单克隆 IgG1κ 抗体。
Ustekinumab (anti-IL-12&IL-23) is an anti-IL-12/IL-23 IgG1κ human monoclonal antibodyPurity
Protein Function
IL-12: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.
Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
IL-23: Associates with IL12B to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to an heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
Ustekinumab (anti-IL-12&IL-23) (Ab175693) - ELISA
Immobilized Recombinant Human IL-12/IL-23 p40 protein (rp181556) at 1.0 μg/mL can bind Ustekinumab (anti-IL-12&IL-23) (Ab175693) with the EC₅₀ of 20.26 ng/mL.
Ustekinumab (anti-IL-12&IL-23) (Ab175693) - SEC
The purity of Ustekinumab (anti-IL-12&IL-23) (Ab175693) is more than 95% verified by HPLC.
| 作用机制 | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | 参考文献 |
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | Ab175693 | |
| 分析证书 | Ab175693 | |
| 分析证书 | Ab175693 |
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