Ziltivekimab (anti-IL-6), IgG 受体和转运体的 Fc 片段抗体

    应用:
  • Animal Model
  • ELISA
  • Flow Cytometry
  • Functional Assay
功能和特点
  • 宿主种属: 人(Human)
  • 种属反应性: 人(Human)
  • 亚型: Human IgG1
  • 偶联: Unconjugated
有货

库存信息

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库存信息

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库存信息

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库存信息

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货号 (SKU) 包装规格 是否现货 价格 数量
Ab175709-100μg
100μg 现货 Stock Image
Ab175709-1mg
1mg 现货 Stock Image
Ab175709-5mg
5mg 现货 Stock Image
Ab175709-10mg
10mg 期货 Stock Image

基本信息

产品名称 Ziltivekimab (anti-IL-6), IgG 受体和转运体的 Fc 片段抗体
别名 泽韦奇单抗 | 齐尔替基单抗(抗 IL-6)
英文别名 Interleukin BSF 2 antibody | B cell differentiation factor antibody | B cell stimulatory factor 2 antibody | B-cell stimulatory factor 2 antibody | BSF 2 antibody | BSF-2 antibody | BSF2 antibody | CDF antibody | CTL differentiation factor antibody | Cyto
规格或纯度 无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属 人(Human)
特异性 IL6
种属反应性 人(Human)
偶联 Unconjugated
作用类型 结合剂
作用机制 IgG 受体和转运体的 Fc 片段抗体

产品属性

克隆类型 重组抗体
Format Whole IgG
亚型 Human IgG1
轻链亚型 kappa
SDS-PAGE 26.4 kDa (Light Chain) & 49.7 kDa (Heavy Chain), under reducing conditions; 175.3 kDa, under non-reducing conditions.
纯化方法 Protein A purified
纯度 >95%
物理外观 Liquid
储存缓冲液 Supplied as a 0.22 μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0.
防腐剂 No
浓度 见COA
储存温度 -80℃储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息 2226654-05-1
分子类型 抗体

图片

Ziltivekimab (anti-IL-6) (Ab175709) - ELISA
Immobilized hu-IL-6 at 2 μg/mL can bind Ziltivekimab (anti-IL-6) (Ab175709) with the EC₅₀ of 103.3 ng/mL.

Ziltivekimab (anti-IL-6) (Ab175709) - SEC
The purity of Ziltivekimab (anti-IL-6) (Ab175709) is more than 95% verified by HPLC.

关联靶点(人)

FCGRT Tclin IgG 受体 FcRn 大亚基 p51(IgG receptor FcRn large subunit p51) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
IL6 Tclin 白细胞介素-6(Interleukin-6) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
FCGRT Tclin IgG receptor FcRn large subunit p51 (445 活性数据)
活性类型 Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID

作用机制

作用机制 Action Type target ID Target Name Target Type Target Organism Binding Site Name 参考文献

安全和危险性(GHS)

技术规格说明书

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
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找到6个结果

批号(Lot Number) 证书类型 日期 货号
ZJ24F1114054 分析证书 24-11-20 Ab175709
ZJ24F1114053 分析证书 24-11-20 Ab175709
ZJ24F1114052 分析证书 24-11-20 Ab175709
ZJ24F0404190 分析证书 24-04-07 Ab175709
ZJ24F0404189 分析证书 24-04-07 Ab175709
ZJ24F0404188 分析证书 24-04-07 Ab175709

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参考文献

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