基本信息

产品名称	Pimivalimab (anti-PD-1), 程序性细胞死亡蛋白 1 抑制剂
别名	匹伐利单抗(抗 PD-1)
英文别名	CD279 antibody \| CD279 antigen antibody \| hPD 1 antibody \| hPD l antibody \| hPD-1 antibody \| hSLE1 antibody \| PD 1 antibody \| PD-1 antibody \| PD1 antibody \| PDCD 1 antibody \| PDCD1 antibody \| PDCD1_HUMAN antibody \| Programmed cell death 1 antibody \| Progr
规格或纯度	无载体, 重组, ExactAb™, 低内毒素, 无叠氮钠, 已验证, 无动物源, ≥95%(SDS-PAGE&SEC-HPLC), 见COA
宿主种属	人(Human)
特异性	PDCD1
种属反应性	人(Human)
偶联	Unconjugated
作用类型	抑制剂
作用机制	程序性细胞死亡蛋白 1 抑制剂

产品属性

克隆类型	重组抗体
Format	Whole IgG
亚型	Human IgG4SP
轻链亚型	kappa
SDS-PAGE	145 kDa
纯化方法	Protein A purified
纯度	>95% (SDS-PAGE&SEC)
物理外观	Liquid
储存缓冲液	Supplied as a 0.22μm filtered solution in 100mM Pro-Ac, 20mM Arg, pH 5.0
防腐剂	No
浓度	见COA
储存温度	-80℃储存,避免反复冻融
运输条件	超低温冰袋运输
稳定性与储存	在 -80℃ 下保存 24 个月。收货后建议分装。避免冷冻/解冻循环。
CAS编号和信息	2293951-22-9
分子类型	抗体

图片

Flow Cytometry: Pimivalimab (anti-PD-1) (Ab182929)

Pimivalimab (anti-PD-1) (Ab182929) - Flow Cytometry
Flow Cytometry analysis of unstimulated (left) or 500 ng/mL Ionomycin (I139530) and 10 ng/mL PMA (P408905) co-stimulated (right) Jurkat cells labelling PD-1 (red) with Pimivalimab (anti-PD-1) (Ab182929) at 0.1 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

ELISA: Pimivalimab (anti-PD-1) (Ab182929)

Pimivalimab (anti-PD-1) (Ab182929) - ELISA
Immobilized Recombinant Human PD-1 protein (rp176241) at 1.0 μg/mL can bind Pimivalimab (anti-PD-1) (Ab182929) with the EC50 of 29.62 ng/mL.